INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION
PROBLEM TO BE SOLVED: To provide an inhibitor of prostaglandin E2 production induced by a stimulant and/or ultraviolet radiation, and to provide a rough skin prophylactic for external use and a skin pigmentation prophylactic for external use, each containing the same. SOLUTION: This pharmaceutical c...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | MASAKI HITOSHI PRESSI GIOVANNA IZUTSU YUKIKO OKANO YURI YAHAGI SHOICHI DAL TOSO ROBERTO |
| description | PROBLEM TO BE SOLVED: To provide an inhibitor of prostaglandin E2 production induced by a stimulant and/or ultraviolet radiation, and to provide a rough skin prophylactic for external use and a skin pigmentation prophylactic for external use, each containing the same. SOLUTION: This pharmaceutical contains as an active ingredient L-α-glycerophospho-D-myo-inositol (GPI) and/or a salt thereof. The compounds have a significant inhibition action against stimulant- or ultraviolet-induced increased production of PG (prostaglandin) E2in epidermal cells, that is, they are effective against a very early inflammatory response mechanism triggered by instantaneous intracellular calcium due to exposure to a stimulant or ultraviolet radiation in epidermal cells. Dermatological external preparations formulated therefrom exhibit the effect of preventing and ameliorating rough skin and the effect of preventing and ameliorating skin pigmentation, blotches, freckles, chloasmas, etc., induced by tanning. COPYRIGHT: (C)2010,JPO&INPIT |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2009269851A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2009269851A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2009269851A3</originalsourceid><addsrcrecordid>eNrjZLDx9PPwdPIM8Q9S8HdTCAjyDw5xdPdx9HPx9FNwNQIJuIQ6h3j6-ykAxRQ8Q4IVQkM8fTyjHEFiPAysaYk5xam8UJqbQcnNNcTZQze1ID8-tbggMTk1L7Uk3ivAyMDA0sjM0sLU0NGYKEUAaN8qOw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION</title><source>esp@cenet</source><creator>MASAKI HITOSHI ; PRESSI GIOVANNA ; IZUTSU YUKIKO ; OKANO YURI ; YAHAGI SHOICHI ; DAL TOSO ROBERTO</creator><creatorcontrib>MASAKI HITOSHI ; PRESSI GIOVANNA ; IZUTSU YUKIKO ; OKANO YURI ; YAHAGI SHOICHI ; DAL TOSO ROBERTO</creatorcontrib><description>PROBLEM TO BE SOLVED: To provide an inhibitor of prostaglandin E2 production induced by a stimulant and/or ultraviolet radiation, and to provide a rough skin prophylactic for external use and a skin pigmentation prophylactic for external use, each containing the same. SOLUTION: This pharmaceutical contains as an active ingredient L-α-glycerophospho-D-myo-inositol (GPI) and/or a salt thereof. The compounds have a significant inhibition action against stimulant- or ultraviolet-induced increased production of PG (prostaglandin) E2in epidermal cells, that is, they are effective against a very early inflammatory response mechanism triggered by instantaneous intracellular calcium due to exposure to a stimulant or ultraviolet radiation in epidermal cells. Dermatological external preparations formulated therefrom exhibit the effect of preventing and ameliorating rough skin and the effect of preventing and ameliorating skin pigmentation, blotches, freckles, chloasmas, etc., induced by tanning. COPYRIGHT: (C)2010,JPO&INPIT</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091119&DB=EPODOC&CC=JP&NR=2009269851A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091119&DB=EPODOC&CC=JP&NR=2009269851A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MASAKI HITOSHI</creatorcontrib><creatorcontrib>PRESSI GIOVANNA</creatorcontrib><creatorcontrib>IZUTSU YUKIKO</creatorcontrib><creatorcontrib>OKANO YURI</creatorcontrib><creatorcontrib>YAHAGI SHOICHI</creatorcontrib><creatorcontrib>DAL TOSO ROBERTO</creatorcontrib><title>INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION</title><description>PROBLEM TO BE SOLVED: To provide an inhibitor of prostaglandin E2 production induced by a stimulant and/or ultraviolet radiation, and to provide a rough skin prophylactic for external use and a skin pigmentation prophylactic for external use, each containing the same. SOLUTION: This pharmaceutical contains as an active ingredient L-α-glycerophospho-D-myo-inositol (GPI) and/or a salt thereof. The compounds have a significant inhibition action against stimulant- or ultraviolet-induced increased production of PG (prostaglandin) E2in epidermal cells, that is, they are effective against a very early inflammatory response mechanism triggered by instantaneous intracellular calcium due to exposure to a stimulant or ultraviolet radiation in epidermal cells. Dermatological external preparations formulated therefrom exhibit the effect of preventing and ameliorating rough skin and the effect of preventing and ameliorating skin pigmentation, blotches, freckles, chloasmas, etc., induced by tanning. COPYRIGHT: (C)2010,JPO&INPIT</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDx9PPwdPIM8Q9S8HdTCAjyDw5xdPdx9HPx9FNwNQIJuIQ6h3j6-ykAxRQ8Q4IVQkM8fTyjHEFiPAysaYk5xam8UJqbQcnNNcTZQze1ID8-tbggMTk1L7Uk3ivAyMDA0sjM0sLU0NGYKEUAaN8qOw</recordid><startdate>20091119</startdate><enddate>20091119</enddate><creator>MASAKI HITOSHI</creator><creator>PRESSI GIOVANNA</creator><creator>IZUTSU YUKIKO</creator><creator>OKANO YURI</creator><creator>YAHAGI SHOICHI</creator><creator>DAL TOSO ROBERTO</creator><scope>EVB</scope></search><sort><creationdate>20091119</creationdate><title>INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION</title><author>MASAKI HITOSHI ; PRESSI GIOVANNA ; IZUTSU YUKIKO ; OKANO YURI ; YAHAGI SHOICHI ; DAL TOSO ROBERTO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2009269851A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2009</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MASAKI HITOSHI</creatorcontrib><creatorcontrib>PRESSI GIOVANNA</creatorcontrib><creatorcontrib>IZUTSU YUKIKO</creatorcontrib><creatorcontrib>OKANO YURI</creatorcontrib><creatorcontrib>YAHAGI SHOICHI</creatorcontrib><creatorcontrib>DAL TOSO ROBERTO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MASAKI HITOSHI</au><au>PRESSI GIOVANNA</au><au>IZUTSU YUKIKO</au><au>OKANO YURI</au><au>YAHAGI SHOICHI</au><au>DAL TOSO ROBERTO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION</title><date>2009-11-19</date><risdate>2009</risdate><abstract>PROBLEM TO BE SOLVED: To provide an inhibitor of prostaglandin E2 production induced by a stimulant and/or ultraviolet radiation, and to provide a rough skin prophylactic for external use and a skin pigmentation prophylactic for external use, each containing the same. SOLUTION: This pharmaceutical contains as an active ingredient L-α-glycerophospho-D-myo-inositol (GPI) and/or a salt thereof. The compounds have a significant inhibition action against stimulant- or ultraviolet-induced increased production of PG (prostaglandin) E2in epidermal cells, that is, they are effective against a very early inflammatory response mechanism triggered by instantaneous intracellular calcium due to exposure to a stimulant or ultraviolet radiation in epidermal cells. Dermatological external preparations formulated therefrom exhibit the effect of preventing and ameliorating rough skin and the effect of preventing and ameliorating skin pigmentation, blotches, freckles, chloasmas, etc., induced by tanning. COPYRIGHT: (C)2010,JPO&INPIT</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_JP2009269851A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS |
| title | INHIBITOR OF PROSTAGLANDIN E2 PRODUCTION AND ITS UTILIZATION |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T18%3A16%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=MASAKI%20HITOSHI&rft.date=2009-11-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EJP2009269851A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |