COATED PARTICULATE CONTAINING PROTON PUMP INHIBITOR

COATED PARTICULATE CONTAINING PROTON PUMP INHIBITOR

PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug release characteristics and can be produced with a good yield, and to provide an orally disintegrating tablet of a benzimidazole proton pump...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: UETSUKI KENJI, KANAI KYOHEI, HIZAKI MASAYA
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a coated particulate for an orally disintegrating tablet containing a benzimidazole proton pump inhibitor, which has good drug release characteristics and can be produced with a good yield, and to provide an orally disintegrating tablet of a benzimidazole proton pump inhibitor having good storage stability. SOLUTION: The coated particulate is obtained by coating a drug layer containing a benzimidazole proton pump inhibitor and a crospovidone fine powder having an average particle size of 3-10 μm on a spherical crystalline cellulose particle and then coating an inert interlayer and an enteric coating layer. The orally disintegrating tablet includes the coated particulate. COPYRIGHT: (C)2010,JPO&INPIT