METHOD OF DETECTING TARGET NUCLEIC ACID
PROBLEM TO BE SOLVED: To provide a method for detecting a target nucleic acid (DNA or RNA) by observing an aqueous solution in which the target nucleic acid is dissolved, under a microscope. SOLUTION: A nucleic acid of an examined object, a pair of probe designed based on the base sequence of the ta...
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Zusammenfassung: | PROBLEM TO BE SOLVED: To provide a method for detecting a target nucleic acid (DNA or RNA) by observing an aqueous solution in which the target nucleic acid is dissolved, under a microscope. SOLUTION: A nucleic acid of an examined object, a pair of probe designed based on the base sequence of the target nucleic acid, and a nucleotide lipid having nucleotide at molecular terminals of a bivalent or trivalent hydrocarbon chain, are dissolved in an aqueous solvent. As the target nucleic acids are present in the aqueous solution, they form complemental nucleic acid base pairs and thereby self-assemble to form fiber, so that the observation of their forms determines whether the target nucleic acid is present or not. COPYRIGHT: (C)2010,JPO&INPIT |
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