METHOD AND COMPOSITION FOR PREDICTING, AND DIAGNOSING MALIGNANT TUMOR

PROBLEM TO BE SOLVED: To provide a method for detecting a chromosomal abnormality using a pathological section because a deficiency or an increase in copies of a complete chromosome or a chromosome fragment, and high-level amplification in a specific region of a genome commonly occur in cancer, and...

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Hauptverfasser: IGARASHI HISAYOSHI, SUGIMURA HARUHIKO, MATSUSHIMA YOSHITAKA, HATTORI NAOHIKO, KIYOSE SHINICHIRO
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for detecting a chromosomal abnormality using a pathological section because a deficiency or an increase in copies of a complete chromosome or a chromosome fragment, and high-level amplification in a specific region of a genome commonly occur in cancer, and Southern blotting or CGH (comparative genomic hybridization) is carried out these days. SOLUTION: An in situ hybridization method for identifying the new chromosomal abnormality associated with various diseases using the pathological section is provided. An in situ hybridization method for identifying the new chromosomal abnormality associated with various diseases is provided. A probe specific for an amplified region of chromosomal region 6p21.3 in pulmonary cancer, and chromosomal region 16p13.3 in gastric cancer is provided. COPYRIGHT: (C)2010,JPO&INPIT