PHARMACEUTICAL COMPOSITION CONTAINING BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a compound having low adverse effects and exhibiting excellent human SGLT inhibiting activity as an active component and useful for the treatment or prevention of hyperglycemia, glucose intolerance, diabetes-related diseases an...
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| creator | OKUYAMA AKIRA OGUCHI MINORU UEDA KENJIRO YOSHIDA MASAO OSUMI JUN OGATA TSUNEAKI IZUMI MASANORI ABE MANABU HONDA TAKESHI |
| description | PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a compound having low adverse effects and exhibiting excellent human SGLT inhibiting activity as an active component and useful for the treatment or prevention of hyperglycemia, glucose intolerance, diabetes-related diseases and diabetic complications caused by type 1 diabetes, type 2 diabetes, pregnancy diabetes and other factors. SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) or its pharmacologically allowable salt [in the formula, R1is a hydrogen atom, an amino group, a mono or di(1-6C alkyl)amino group, a 1-6C alkyl group, a hydroxy(1-6C alkyl) group or the like; R2is a hydrogen atom, a halogen atom or a 1-6C alkyl group; R3is a 1-6C alkyl group, a hydroxy(1-6C alkyl) group, a 1-6C alkyl group or the like; R4is a hydrogen atom, a 1-6C alkyl group, a 2-7C acyl group, a 1-6C alkoxycarbonyl group or the like; R5, R6, R7and R8may be the same or different and each represents a hydrogen atom or a 1-6C alkyl group (wherein, R5, R6, R7and R8are not hydrogen atoms at the same time); R9is a halogen atom; n is 0-4; and X is CH or N]. COPYRIGHT: (C)2009,JPO&INPIT |
| format | Patent |
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SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) or its pharmacologically allowable salt [in the formula, R1is a hydrogen atom, an amino group, a mono or di(1-6C alkyl)amino group, a 1-6C alkyl group, a hydroxy(1-6C alkyl) group or the like; R2is a hydrogen atom, a halogen atom or a 1-6C alkyl group; R3is a 1-6C alkyl group, a hydroxy(1-6C alkyl) group, a 1-6C alkyl group or the like; R4is a hydrogen atom, a 1-6C alkyl group, a 2-7C acyl group, a 1-6C alkoxycarbonyl group or the like; R5, R6, R7and R8may be the same or different and each represents a hydrogen atom or a 1-6C alkyl group (wherein, R5, R6, R7and R8are not hydrogen atoms at the same time); R9is a halogen atom; n is 0-4; and X is CH or N]. 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SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) or its pharmacologically allowable salt [in the formula, R1is a hydrogen atom, an amino group, a mono or di(1-6C alkyl)amino group, a 1-6C alkyl group, a hydroxy(1-6C alkyl) group or the like; R2is a hydrogen atom, a halogen atom or a 1-6C alkyl group; R3is a 1-6C alkyl group, a hydroxy(1-6C alkyl) group, a 1-6C alkyl group or the like; R4is a hydrogen atom, a 1-6C alkyl group, a 2-7C acyl group, a 1-6C alkoxycarbonyl group or the like; R5, R6, R7and R8may be the same or different and each represents a hydrogen atom or a 1-6C alkyl group (wherein, R5, R6, R7and R8are not hydrogen atoms at the same time); R9is a halogen atom; n is 0-4; and X is CH or N]. 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SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) or its pharmacologically allowable salt [in the formula, R1is a hydrogen atom, an amino group, a mono or di(1-6C alkyl)amino group, a 1-6C alkyl group, a hydroxy(1-6C alkyl) group or the like; R2is a hydrogen atom, a halogen atom or a 1-6C alkyl group; R3is a 1-6C alkyl group, a hydroxy(1-6C alkyl) group, a 1-6C alkyl group or the like; R4is a hydrogen atom, a 1-6C alkyl group, a 2-7C acyl group, a 1-6C alkoxycarbonyl group or the like; R5, R6, R7and R8may be the same or different and each represents a hydrogen atom or a 1-6C alkyl group (wherein, R5, R6, R7and R8are not hydrogen atoms at the same time); R9is a halogen atom; n is 0-4; and X is CH or N]. COPYRIGHT: (C)2009,JPO&INPIT</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | PHARMACEUTICAL COMPOSITION CONTAINING BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE |
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