PHARMACEUTICAL COMPOSITION CONTAINING BENZYL PHENYL GLUCOPYRANOSIDE DERIVATIVE
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a compound having low adverse effects and exhibiting excellent human SGLT inhibiting activity as an active component and useful for the treatment or prevention of hyperglycemia, glucose intolerance, diabetes-related diseases an...
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Zusammenfassung: | PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a compound having low adverse effects and exhibiting excellent human SGLT inhibiting activity as an active component and useful for the treatment or prevention of hyperglycemia, glucose intolerance, diabetes-related diseases and diabetic complications caused by type 1 diabetes, type 2 diabetes, pregnancy diabetes and other factors. SOLUTION: The pharmaceutical composition contains a compound expressed by general formula (I) or its pharmacologically allowable salt [in the formula, R1is a hydrogen atom, an amino group, a mono or di(1-6C alkyl)amino group, a 1-6C alkyl group, a hydroxy(1-6C alkyl) group or the like; R2is a hydrogen atom, a halogen atom or a 1-6C alkyl group; R3is a 1-6C alkyl group, a hydroxy(1-6C alkyl) group, a 1-6C alkyl group or the like; R4is a hydrogen atom, a 1-6C alkyl group, a 2-7C acyl group, a 1-6C alkoxycarbonyl group or the like; R5, R6, R7and R8may be the same or different and each represents a hydrogen atom or a 1-6C alkyl group (wherein, R5, R6, R7and R8are not hydrogen atoms at the same time); R9is a halogen atom; n is 0-4; and X is CH or N]. COPYRIGHT: (C)2009,JPO&INPIT |
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