CIS-FTC OF POLYMORPH AND OTHER CRYSTAL FORM
PROBLEM TO BE SOLVED: To provide FTC of new polymorphic and other crystal form. SOLUTION: A solid phase of amorphous (-)-FTC and (-)-cis-FTC called II and III(-)-cis-FTC which is distinguishable from I(-)-cis-FTC by its powder X-ray diffraction pattern, heat characteristic and production methods is...
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| creator | LAW DEVALINA HU YUERONG PHARES KENNETH R |
| description | PROBLEM TO BE SOLVED: To provide FTC of new polymorphic and other crystal form. SOLUTION: A solid phase of amorphous (-)-FTC and (-)-cis-FTC called II and III(-)-cis-FTC which is distinguishable from I(-)-cis-FTC by its powder X-ray diffraction pattern, heat characteristic and production methods is provided. A hydrated crystal form of (±)-cis-FTC (that is, racemic cis-FTC) which is distinguishable from other form of FTC by its powder X-ray diffraction pattern, heat characteristic and production methods in a similar way, and a dehydrated form of the hydrate are also provided. These forms of FTC can be used for producing other forms of FTC or for a pharmaceutical composition. These forms are particularly desirably used for treating HIV or hepatitis B. COPYRIGHT: (C)2009,JPO&INPIT |
| format | Patent |
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SOLUTION: A solid phase of amorphous (-)-FTC and (-)-cis-FTC called II and III(-)-cis-FTC which is distinguishable from I(-)-cis-FTC by its powder X-ray diffraction pattern, heat characteristic and production methods is provided. A hydrated crystal form of (±)-cis-FTC (that is, racemic cis-FTC) which is distinguishable from other form of FTC by its powder X-ray diffraction pattern, heat characteristic and production methods in a similar way, and a dehydrated form of the hydrate are also provided. These forms of FTC can be used for producing other forms of FTC or for a pharmaceutical composition. These forms are particularly desirably used for treating HIV or hepatitis B. 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SOLUTION: A solid phase of amorphous (-)-FTC and (-)-cis-FTC called II and III(-)-cis-FTC which is distinguishable from I(-)-cis-FTC by its powder X-ray diffraction pattern, heat characteristic and production methods is provided. A hydrated crystal form of (±)-cis-FTC (that is, racemic cis-FTC) which is distinguishable from other form of FTC by its powder X-ray diffraction pattern, heat characteristic and production methods in a similar way, and a dehydrated form of the hydrate are also provided. These forms of FTC can be used for producing other forms of FTC or for a pharmaceutical composition. These forms are particularly desirably used for treating HIV or hepatitis B. COPYRIGHT: (C)2009,JPO&INPIT</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CIS-FTC OF POLYMORPH AND OTHER CRYSTAL FORM |
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