METHOD AND KIT FOR DETECTING COMBINED THERAPEUTIC EFFECT OF INTERFERON AND RIBAVIRIN

PROBLEM TO BE SOLVED: To provide a method by which the effectiveness of combined therapy of interferon and ribavirin can be determined before starting the therapy or at an early stage after starting the therapy. SOLUTION: The method for detecting the combined therapeutic effect of the interferon and the ribavirin uses the difference in expression levels of a specific biomaterial discovered by the following comparison as an index exhibiting the effectiveness of the combined therapy of the interferon and the ribavirin by comparing the expression levels of the specific biomaterial in each cell before and after administration of the interferon and the ribavirin to detect the combined therapeutic effects of the interferon and the ribavirin in a testee of a carrier of hepatitis C virus. The specific biomaterial is at least one selected from the group consisting of ANXA3, PCNA, LMNB1, PAK1, 4EBP1, KARS, PSME2, ENO1, STAT1, PHB, SP-100, and PPP1CB. COPYRIGHT: (C)2009,JPO&INPIT