DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME

PROBLEM TO BE SOLVED: To provide a dendritic polymer and a magnetic resonance imaging contrast agent employing the same. SOLUTION: The magnetic resonance imaging contrast agent includes the dendritic polymer having a structure represented by formula (I), wherein P is represented by formula (1), and...

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Hauptverfasser:	THIRUMALAI DHAKSHANAMURTHY, RIN SHINEKI, O SENCHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a dendritic polymer and a magnetic resonance imaging contrast agent employing the same. SOLUTION: The magnetic resonance imaging contrast agent includes the dendritic polymer having a structure represented by formula (I), wherein P is represented by formula (1), and 1 is a number of ≥1 and j is a number of ≥2; D is a 3-30C dendritic moiety having n oxygen residues, and n is a number of ≥3 and i is an integer of >1; X is a 3-30C moiety having bi-functionality; Z is independent and includes a 3-20C moiety having a plurality of functional groups, wherein the functional groups are selected from a group consisting of carbonyl, carboxyl, amine, ester, amide, or chelate group, and Z respectively bonds with X by a group represented by formula (2) or (3); and L is a metal cation. COPYRIGHT: (C)2009,JPO&INPIT