NEW PYRAZINE DERIVATIVE OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR THE SALT AND INTERMEDIATE FOR THE PRODUCTION OF BOTH

PROBLEM TO BE SOLVED: To provide intermediates for production of pyrazine derivatives or salts thereof having excellent antiviral activity and useful as remedies for viral infection. SOLUTION: The fluoropyrazine derivatives represented by the general formula or salts thereof (in the formula R21is a...

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Bibliographische Detailangaben
Hauptverfasser:	UEHARA SAYURI, HAMAMOTO SHOICHI, EGAWA HIROYUKI, FURUTA YOSUKE, YONEZAWA KENJI, SUGITA ATSUSHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide intermediates for production of pyrazine derivatives or salts thereof having excellent antiviral activity and useful as remedies for viral infection. SOLUTION: The fluoropyrazine derivatives represented by the general formula or salts thereof (in the formula R21is a carbamoyl group, a carboxy group, etc., R22is a (protected) hydroxy group, an amino group, etc.) are disclosed. The compound is useful as an intermediate for an industrial production of the fluoropyrazinecarboxamide represented by 6-fluoro-3-hydroxy-2-pyrazinecarboxamide. COPYRIGHT: (C)2009,JPO&INPIT