PROPHYLACTIC OR THERAPEUTIC AGENT FOR DISEASE ASSOCIATED WITH HYPOFUNCTION OF NOS

PROBLEM TO BE SOLVED: To provide a therapeutic agent for effectively preventing or ameliorating diseases caused by hypofunction of NOS (NO synthase). SOLUTION: The present invention provides a pharmaceutical composition for preventing and/or treating diseases associated with hypofunction of NOS, com...

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Bibliographische Detailangaben
Hauptverfasser: OKAMURA MIKIO, SHINTAKU HARUO, ISHIHARA TAKABUMI, YOSHIKAWA JUNICHI, KANAYAMA YOSHIHARU
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a therapeutic agent for effectively preventing or ameliorating diseases caused by hypofunction of NOS (NO synthase). SOLUTION: The present invention provides a pharmaceutical composition for preventing and/or treating diseases associated with hypofunction of NOS, comprising as an effective ingredient, a compound of the formula: wherein R1and R2each represents a hydrogen atom or, form together a single bond, while R3represents -CH(OH)CH(OH)CH3, -CH(OCOCH3)CH(OCOCH3)CH3, -CH3, -CH2OH, or a phenyl group when R1and R2each represents a hydrogen atom, or -COCH(OH)CH3when R1and R2form together a single bond, or a pharmaceutically acceptable salt thereof. COPYRIGHT: (C)2009,JPO&INPIT