SPHERICAL PARTICLE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide spherical particles equipped with advantageous points such as a high general purpose property without restricting the use of active ingredients and hardly getting abrasion on forming its preparation, and having less reduction of its bioavailability, and a method for...

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1. Verfasser:	TAKAHASHI TERUMI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide spherical particles equipped with advantageous points such as a high general purpose property without restricting the use of active ingredients and hardly getting abrasion on forming its preparation, and having less reduction of its bioavailability, and a method for producing the same. SOLUTION: The spherical particles is characterized by containing a sugar alcohol, crystalline cellulose and/or powdery cellulose and having (50:50) to (90:10) mass ratio of the sugar alcohol to the crystalline cellulose and/or powdery cellulose, a 75 to 250 μm particle diameter, ≥0.8 sphericity and ≥0.6 g/ml bulk density. Also, the method for producing the spherical particles is characterized by comprising a granulation process of granulating by spraying liquid on the sugar alcohol having a ≤40 μm mean particle diameter, crystalline cellulose and/or powdery cellulose having a ≤50 μm mean particle diameter while rolling. COPYRIGHT: (C)2009,JPO&INPIT