ANTAGONISTIC SELECTIVE-BINDING FACTOR OF OSTEOPROTEGERIN-BINDING PROTEIN

PROBLEM TO BE SOLVED: To provide a selective binding factor of an osteoprotegerin-binding protein (OPGbp), and antibodies and antigen-binding domains which selectively bind to the OPGbp and capable of being used to prevent and treat loss of bone mass. SOLUTION: The nucleic acid molecules capable of...

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Hauptverfasser:	SULLIVAN JOHN KEVIN, BOYLE WILLIAM J, DESHPANDE RAJENDRA V, HITZ ANNA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a selective binding factor of an osteoprotegerin-binding protein (OPGbp), and antibodies and antigen-binding domains which selectively bind to the OPGbp and capable of being used to prevent and treat loss of bone mass. SOLUTION: The nucleic acid molecules capable of encoding antibodies and antigen-binding domains selectively binding to the OPGbp and capable of being used to prevent and treat the loss of the bone mass are provided, and expression vectors and host cells for production of them are also provided. COPYRIGHT: (C)2009,JPO&INPIT