SUBSTITUTED PYRAZOLYL COMPOUND FOR TREATING INFLAMMATION

PROBLEM TO BE SOLVED: To provide a substituted pyrazolyl derivative for treating cancer, inflammation and inflammation-associated disorders such as arthritis. SOLUTION: A compound having a structural formula expressed by figure is cited as an example. The compound is 1-ä4-[(aminothio)peroxy]phenyl}-...

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Hauptverfasser: METZ SUZANNE, MOHLER SCOTT B, CLARE MICHAEL, HAMPER BRUCE C, BERGMANIS ARIJA A, BONAFOUX DOMINIQUE, HUANG HE, LIAO SUBO, GENG LIFENG, XU XIANGDONG, STEALEY MICHAEL A, HOUDEK STEPHEN C, HAGEN TIMOTHY J, VAZQUEZ MICHAEL L, WEIER RICHARD M, OWEN THOMAS J, HANSON GUNNAR J, OBURN DAVID S, SCATES ANGELA M, PARTIS RICHARD A, KOSZYK FRANCIS J, FLETCHER THERESA R, IULA DONNA M, LIAO SHUYUAN, WOLFSON SERGE G, NGUYEN MARIA, LENNON PATRICK J, CRICH JOYCE Z, TOLLEFSON MICHAEL B
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Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a substituted pyrazolyl derivative for treating cancer, inflammation and inflammation-associated disorders such as arthritis. SOLUTION: A compound having a structural formula expressed by figure is cited as an example. The compound is 1-ä4-[(aminothio)peroxy]phenyl}-8-nitro-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide. COPYRIGHT: (C)2009,JPO&INPIT