NEW HETEROARYLPIPERIDINE DERIVATIVE

NEW HETEROARYLPIPERIDINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a heteroarylpiperidine derivative having excellent stearoyl-CoA desaturase inhibition or its pharmacologically acceptable salt. SOLUTION: The heteroarylpiperidine derivative is represented by formula (I) (wherein A is a group represented by the formula: -CONHR1or a g...

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Hauptverfasser: OKUYAMA AKIRA, KIYOZUKA YOHEI, KONISHI MASAHIRO, OSUMI JUN, OGATA TSUNEAKI, UTO YOSHIICHI, KURIKAWA SHINYA, KURATA HITOSHI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a heteroarylpiperidine derivative having excellent stearoyl-CoA desaturase inhibition or its pharmacologically acceptable salt. SOLUTION: The heteroarylpiperidine derivative is represented by formula (I) (wherein A is a group represented by the formula: -CONHR1or a group represented by the formula -ER2; R3is hydrogen or the like; R4is hydrogen or the like; R5is a 6-10C aryl group which may be independently substituted with 1 to 5 substituents or the like; R6is hydrogen or a halogen; V is nitrogen or the like; W is nitrogen or the like; Y is a carbonyl group or the like; m is 0, 1 or 2; and n is 0, 1 or 2) and includes its pharmacologically acceptable salt. COPYRIGHT: (C)2009,JPO&INPIT