METHOD FOR SCREENING PEPTIDE DISPLAY LIBRARY BY USING MINICELL DISPLAY

PROBLEM TO BE SOLVED: To provide a method of minicell display, having a significant advantageous point in screening a peptide library for a candidate of bonding and effectively adjusting a specific biological process. SOLUTION: This method is based on the small anuclear minicell for increasing diver...

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1. Verfasser:	ASHKAR SAMY
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method of minicell display, having a significant advantageous point in screening a peptide library for a candidate of bonding and effectively adjusting a specific biological process. SOLUTION: This method is based on the small anuclear minicell for increasing diversity in preparing unique sequences to be screened and also increasing the size of the peptides to be screened. An in vitro mutagenesis (in the level of protein synthesis) and a DNA replication increase the diversity of the libraries to be screened and therefore, substantially increase the number of potential peptides adjustable a specific biological response or mechanism. COPYRIGHT: (C)2009,JPO&INPIT