SHEET INCLUDING CARDIOMYOCYTE

PROBLEM TO BE SOLVED: To provide a method for acquiring a large amount of cardiomyocytes, a sheet including cardiomyocytes, and also a method for screening substances for promoting differentiation into the cardiomyocytes. SOLUTION: In a method, Fatty tissue-derived stem cells are cultivated under pr...

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Bibliographische Detailangaben
Hauptverfasser: SAWA YOSHIKI, MATSUYAMA AKIBUMI, OKURA HANAYUKI, KOMODA HIROSHI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for acquiring a large amount of cardiomyocytes, a sheet including cardiomyocytes, and also a method for screening substances for promoting differentiation into the cardiomyocytes. SOLUTION: In a method, Fatty tissue-derived stem cells are cultivated under presence of DMSO or OP9 cultivation supernatant and differentiated into cardiomyocytes, and then, the sheet including cardiomyocytes is formed. In the method for screening the differentiation promoting substances, candidate substances for promoting the differentiation into cardiomyocytes are added in cultivating fatty tissue-derived stem cells so as to screen the differentiation promoting substances. COPYRIGHT: (C)2009,JPO&INPIT