PURIFIED MULTIMERASE

PROBLEM TO BE SOLVED: To provide an enzyme activity of processing von Willebrand Factor (vWF) in a physiologic manner by protein hydrolysis and as necessary decomposing vWF and to provide a preparation containing such enzyme activity. SOLUTION: A purified multimerase has an indirect or direct proteo...

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Hauptverfasser: TURECEK PETER, FURLAN MIHA, LAEMMLE BERNHARD, HANSUUPEETAA SHIYUBUARUTSU, YOHAN AIBURU
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creator TURECEK PETER
FURLAN MIHA
LAEMMLE BERNHARD
HANSUUPEETAA SHIYUBUARUTSU
YOHAN AIBURU
description PROBLEM TO BE SOLVED: To provide an enzyme activity of processing von Willebrand Factor (vWF) in a physiologic manner by protein hydrolysis and as necessary decomposing vWF and to provide a preparation containing such enzyme activity. SOLUTION: A purified multimerase has an indirect or direct proteolytic activity, can convert vWF having a singlet structure into vWF having a satellite structure and is active in the presence of the serine protease inhibitor diisopropyl fluorophosphate (DFP) or the calpain protease inhibitor Z-Leu-Leu-Tyr-CHN2, and a preparation containing the multimerase is provided. COPYRIGHT: (C)2009,JPO&INPIT
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title PURIFIED MULTIMERASE
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