PURIFIED MULTIMERASE

PROBLEM TO BE SOLVED: To provide an enzyme activity of processing von Willebrand Factor (vWF) in a physiologic manner by protein hydrolysis and as necessary decomposing vWF and to provide a preparation containing such enzyme activity. SOLUTION: A purified multimerase has an indirect or direct proteo...

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Hauptverfasser:	TURECEK PETER, FURLAN MIHA, LAEMMLE BERNHARD, HANSUUPEETAA SHIYUBUARUTSU, YOHAN AIBURU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an enzyme activity of processing von Willebrand Factor (vWF) in a physiologic manner by protein hydrolysis and as necessary decomposing vWF and to provide a preparation containing such enzyme activity. SOLUTION: A purified multimerase has an indirect or direct proteolytic activity, can convert vWF having a singlet structure into vWF having a satellite structure and is active in the presence of the serine protease inhibitor diisopropyl fluorophosphate (DFP) or the calpain protease inhibitor Z-Leu-Leu-Tyr-CHN2, and a preparation containing the multimerase is provided. COPYRIGHT: (C)2009,JPO&INPIT