AMINOALCOHOL DERIVATIVE AND IMMUNOSUPPRESSIVE AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT

AMINOALCOHOL DERIVATIVE AND IMMUNOSUPPRESSIVE AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT

PROBLEM TO BE SOLVED: To provide an aminoalcohol derivative having excellent immunosuppressive activity and exhibiting fewer side effects. SOLUTION: The aminoalcohol derivative having a mechanism of action different from those of an antimetabolite and a calcineurin inhibitor, and being represented b...

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Bibliographische Detailangaben
Hauptverfasser: KONO YASUSHI, FUJII KIYOSHI, ANDOU NAOKI
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an aminoalcohol derivative having excellent immunosuppressive activity and exhibiting fewer side effects. SOLUTION: The aminoalcohol derivative having a mechanism of action different from those of an antimetabolite and a calcineurin inhibitor, and being represented by general formula (1) (wherein, R1is a chlorine atom, a 1-3C linear alkyl group or a trifluoromethyl group; R2is a fluorine atom or a chlorine atom; R3is a 1-3C linear alkyl group; X is SO or SO2; and n is 2 or 3), or a pharmacologically acceptable salt or a hydrate thereof is provided. COPYRIGHT: (C)2009,JPO&INPIT