METHOD FOR ADMINISTERING AZITHROMYCIN

PROBLEM TO BE SOLVED: To provide a dosage form of administering azithromycin to a patient which just took foods. SOLUTION: The present invention provides an oral dosage form of azithromycin which can administer to mammals which took foods and contains azithromycin and substantially does not exhibit negative alimentary effect. Solubility of azithromycin is at least about 90% within about 30 min when dosage form in an amount corresponding to 250 mg azithromycin is tested by a method USP-711 in a USP-2 dissolution apparatus with a paddle rotating under the stringent conditions that correspond the following indices: 900 mL phosphoric acid buffer, pH 6.0, at 37°C and at 100 rpm, with the proviso that the dosage form is not a capsule and contains an alkaline earth metal oxide or hydroxide in an amount less than taste-blocking amount and does not exhibit adverse effect of foods. COPYRIGHT: (C)2009,JPO&INPIT