LUNG CANCER MODEL ANIMAL AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a lung cancer model animal having EGFR (epidermal growth factor receptor) gene mutation, and to provide its use. SOLUTION: A lung cancer model animal is such as to be transferred with an expression vector containing a lung surfactant protein C promoter and a mouse mu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	OSAWA MASAHIRO, RAI KANMEI, TAKADA MINORU, OHASHI YOSHIAKI, TANIMOTO MITSUNE, KIURA KATSUYUKI, FUJIWARA YOSHIRO, HIRANO TSUGUNORI
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TESTING TRAPPING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a lung cancer model animal having EGFR (epidermal growth factor receptor) gene mutation, and to provide its use. SOLUTION: A lung cancer model animal is such as to be transferred with an expression vector containing a lung surfactant protein C promoter and a mouse mutated EGFR gene. Another version of this model animal is such as to be transferred with an expression vector containing a lung surfactant protein C promoter and a human mutated EGFR gene. A method for screening candidate substance(s) for treating lung cancer comprising using either one of the above model animals or the tissue or cells derived therefrom is also provided. COPYRIGHT: (C)2008,JPO&INPIT