AGENT FOR MODIFICATION OF SH GROUP

PROBLEM TO BE SOLVED: To provide an agent for the modification of an SH group (thiol group) and a cell-protecting agent, which selectively reacts particularly with a highly reactive SH group in an intracellular environment where SH-containing proteins having various types of reactivity are present i...

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Bibliographische Detailangaben
Hauptverfasser:	AKAIKE TAKAAKI, ARIMOTO HIROICHI, SAWA TOMOHIRO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an agent for the modification of an SH group (thiol group) and a cell-protecting agent, which selectively reacts particularly with a highly reactive SH group in an intracellular environment where SH-containing proteins having various types of reactivity are present in a mixed state. SOLUTION: The agent for the modification of an SH group and the cell-protecting agent comprise a 8-nitroguanosine derivative. COPYRIGHT: (C)2008,JPO&INPIT