BUTOXYANILINE DERIVATIVE

BUTOXYANILINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a compound having inhibitory action on Na+/Ca2+exchangers and useful as a medicine. SOLUTION: The compound is a butoxyaniline derivative represented by general formula (I) (wherein, Ar is a phenyl or an aromatic heterocyclic group; D is a single bond or a methylene;...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TAKAYANAGI KOICHI, MIZUNO YUSUKE, NOMIYAMA KENTA
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a compound having inhibitory action on Na+/Ca2+exchangers and useful as a medicine. SOLUTION: The compound is a butoxyaniline derivative represented by general formula (I) (wherein, Ar is a phenyl or an aromatic heterocyclic group; D is a single bond or a methylene; R1is a hydrogen atom, a lower alkyl group, a lower alkoxy group or the like; R2and R3are each a hydrogen atom or joined together to form -(CH2)2-; R4is a halogen atom, a cyan group, a lower alkyl or lower alkoxy group; and a dotted line denotes a double or triple bond). Pharmaceutically acceptable salts of the compound are also provided. COPYRIGHT: (C)2008,JPO&INPIT