PEGYLATED ION CHANNEL MODULATING COMPOUND

PROBLEM TO BE SOLVED: To satisfy demands for identification of a new treatment on anti-arrhythmia on both of the venticular arrhythmia and atrial arrhythmia. SOLUTION: The invention relates to PEGlyated derivatives comprising one or more PEG moieties attached to an ion channel modulating compound. T...

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Hauptverfasser:	PLOUVIER BERTRAND M C, CHOU DOUG TA HUANG, CHOI LEWIS SIU LEUNG, EZRIN ALAN M, CHEU ELIZABETH L S, YIFRU AREGAHEGN, DAVIDOFF ALLEN W, JUNG GRACE
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To satisfy demands for identification of a new treatment on anti-arrhythmia on both of the venticular arrhythmia and atrial arrhythmia. SOLUTION: The invention relates to PEGlyated derivatives comprising one or more PEG moieties attached to an ion channel modulating compound. The PEG moiety is attached to the ion channel modulating compound via a linker, in an embodiment. The compound is attached via substitution of bonding to the PEG moieties of the compounds with any atomic valence. COPYRIGHT: (C)2008,JPO&INPIT