BLOOD PURIFIER AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a blood purifier which is easy to handle and fully exerts permeation capacity of hollow fiber membranes, and also to provide a method for producing the same. SOLUTION: The blood purifier 1 comprises a casing filled with a hollow fiber bundle made by bundling hollow fiber membranes. The hollow fiber membrane contains, as a main membrane material, a polymer alloy membrane made of a polyarylate resin and a polyethersulfone resin. In the blood purifier, blood contacting parts of the hollow fiber membrane are hydrophilized by means of polyvinylpyrrolidone as a hydrophilic polymer. The property of the hollow fiber membrane bundle is adjusted in such a way that when an endotoxin solution of 1,000 EU/L is filtered out for two hours at a flow rate of 50 ml/min from outside to the inside of a hollow fiber membrane having a membrane area of 0.15 m2, endotoxin concentration of filtrate is 1.0 EU/L or less. In addition, water content of the hollow fiber membrane is adjusted to 2.0-15.0 g per 1 m2of the hollow fiber membrane. COPYRIGHT: (C)2008,JPO&INPIT