HUMAN CTLA-8 AND USES OF CTLA-8-RELATED PROTEINS

PROBLEM TO BE SOLVED: To provide new methods for identifying novel cytokines and other secretion factors and to isolate polynucleotides encoding them, and to provide uses of the cytokines. SOLUTION: Polynucleotides encoding human CTLA-8 and human CTLA-8 polypeptides are disclosed. The inhibition of...

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Hauptverfasser: MI SHA, JACOBS KENNETH, CARLIN MCKEOUGH, GOLDEN-FLEET MARGARET, KELLEHER KERRY, GIANNOTTI JOANN, GOLDMAN SAMUEL, PITTMAN DEBRA, NEBEN STEVEN
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creator MI SHA
JACOBS KENNETH
CARLIN MCKEOUGH
GOLDEN-FLEET MARGARET
KELLEHER KERRY
GIANNOTTI JOANN
GOLDMAN SAMUEL
PITTMAN DEBRA
NEBEN STEVEN
description PROBLEM TO BE SOLVED: To provide new methods for identifying novel cytokines and other secretion factors and to isolate polynucleotides encoding them, and to provide uses of the cytokines. SOLUTION: Polynucleotides encoding human CTLA-8 and human CTLA-8 polypeptides are disclosed. The inhibition of angiogenesis, inhibition of proliferation of vascular endothelial cells, inhibition of tumor growth, inhibition of angiogenesis-dependent tissue growth, proliferation of myeloid cells or progenitors, proliferation of erythroid cells or progenitors, proliferation of lymphoid cells or progenitors, induction of IFNγ production, the induction of IL-3 production and induction of GM-CSF production are effectively carried out in a subject by using the polynucleotides and the polypeptides. COPYRIGHT: (C)2008,JPO&INPIT
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recordid cdi_epo_espacenet_JP2008131942A
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title HUMAN CTLA-8 AND USES OF CTLA-8-RELATED PROTEINS
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