NEW HUMAN NK3 RECEPTOR-SELECTIVE ANTAGONIST COMPOUND, METHOD FOR OBTAINING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

PROBLEM TO BE SOLVED: To provide a new selective human NK3 receptor antagonist compound for preparing drugs useful for treating psychiatric diseases, diseases of psychosomatic origin, hypertension and, in general, any central or peripheral pathological conditions in which NKB (neurokinin B) and the NK3 receptor are involved in interneuronal regulatory processes, to provide a method for obtaining the compound and to provide a pharmaceutical composition in which the compound is present as an active ingredient. SOLUTION: The compound is represented by formula (I) (wherein, R1represents hydrogen; R2represents methyl or the like; Ar1represents phenyl, thienyl, naphthyl or the like; T represents a group -CH2- group, -CO- group, -COO- group or the like; A represents a direct bond, vinylene group or the like; and Z represents an optionally substituted, monocyclic, bicyclic or tricyclic aromatic or heteroaromatic group). The method for preparing the compound and the pharmaceutical composition comprising the compound are also provided. COPYRIGHT: (C)2008,JPO&INPIT