PREPARATION OF PREGABALIN AND RELATED COMPOUND

PROBLEM TO BE SOLVED: To provide a commercially feasible method for preparing pregabalin. SOLUTION: A method for preparing (2)-(+)-3-aminomethyl-5-methyl-hexanoic acid (pregabalin) and structurally related compounds via the enzymatical kinetic resolution are provided is provided. COPYRIGHT: (C)2008,...

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Hauptverfasser:	MARTINEZ CARLOS A, DUMOND YVES RENE, KELLEHER PATRICK G T, HU SHANGHUI, TAO JUNHUA, TULLY WILLIAM EUGENE
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a commercially feasible method for preparing pregabalin. SOLUTION: A method for preparing (2)-(+)-3-aminomethyl-5-methyl-hexanoic acid (pregabalin) and structurally related compounds via the enzymatical kinetic resolution are provided is provided. COPYRIGHT: (C)2008,JPO&INPIT