HETEROCYCLIC COMPOUND AND ITS MANUFACTURING AND USING METHODS
PROBLEM TO BE SOLVED: To provide a compound for treating vascular obliterating pathological state, specially for treating restenosis. SOLUTION: A compound expressed by formula (I), and a composition containing a compound effective for moderating inflammatory-responses, occurring from such as AGE (ad...
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| creator | PILLARISETTI RAM PAL MANOJIT RAO YELESWARAPU KOTESWAR RAO KALLEDA SRINIVASA SHARMA VEDULA MANOHAR VENKATESWARLU AKELLA PADAKANTI SRINIVAS |
| description | PROBLEM TO BE SOLVED: To provide a compound for treating vascular obliterating pathological state, specially for treating restenosis. SOLUTION: A compound expressed by formula (I), and a composition containing a compound effective for moderating inflammatory-responses, occurring from such as AGE (advanced glycated end products) and glycated protein accumulation, and/or methods therefor are provided. A composition containing a compound effective for moderating smooth muscle cell proliferation, and diseases or sicknesses related to it, and/or methods therefor, are also provided. The invention provides a compound and a composition for inhibiting the smooth muscle cell proliferation, which may be mediated by pro-inflammatory cytokines such as IL-6, IL-1, TNF-α and MCP-1, or by inducing the expression of perlecan or heparin sulfate proteoglycans (HSPG). COPYRIGHT: (C)2008,JPO&INPIT |
| format | Patent |
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SOLUTION: A compound expressed by formula (I), and a composition containing a compound effective for moderating inflammatory-responses, occurring from such as AGE (advanced glycated end products) and glycated protein accumulation, and/or methods therefor are provided. A composition containing a compound effective for moderating smooth muscle cell proliferation, and diseases or sicknesses related to it, and/or methods therefor, are also provided. The invention provides a compound and a composition for inhibiting the smooth muscle cell proliferation, which may be mediated by pro-inflammatory cytokines such as IL-6, IL-1, TNF-α and MCP-1, or by inducing the expression of perlecan or heparin sulfate proteoglycans (HSPG). 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HETEROCYCLIC COMPOUND AND ITS MANUFACTURING AND USING METHODS |
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