SUBSTITUTED MORPHOLINE COMPOUND FOR TREATING CENTRAL NERVOUS SYSTEM DISORDER

PROBLEM TO BE SOLVED: To provide a substituted morpholine compound for treating central nervous system disorders. SOLUTION: The compound expressed by formula (I) or its pharmaceutically permissible salts are provided. In the formula, A expresses O or S; X expresses a heterocyclic ring; R1to R5expres...

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Hauptverfasser:	GRAY DAVID LAWRENCE FIRMAN, XU WENJIAN, BARTA NANCY SUE, GLASE SHELLY ANN, SIMONS LLOYD JEROME, REICHARD GREGORY ADAM
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a substituted morpholine compound for treating central nervous system disorders. SOLUTION: The compound expressed by formula (I) or its pharmaceutically permissible salts are provided. In the formula, A expresses O or S; X expresses a heterocyclic ring; R1to R5express each H, a 1-6C alkyl, an aryl, a 3-8C cycloalkyl, a 1-6C alkenyl, a 5-8C cycloalkenyl, a (CH2)n-3-8C cycloalkyl, a 1-6C alkoxy, an O-aryl or the like; * expresses a first chiral center; Ð expresses a second chiral center. COPYRIGHT: (C)2008,JPO&INPIT