ANTICOAGULANT AGENT USEFUL IN TREATMENT OF THROMBOSIS

PROBLEM TO BE SOLVED: To provide an amino acid sequence in an immune globulin H-chain or L-chain complementary-deciding area originating from anticoagulation factor monoclonal antibody, or a nucleic acid molecule encoding the area. SOLUTION: This invention provides an amino acid sequence selected fr...

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Hauptverfasser: FEUERSTEIN GIORA ZEEV, NICHOLS ANDREW JOHN, CHURCH WILLIAM ROBERT, PATEL ARUNBHAI HARIBHAI, BLACKBURN MICHAEL NEAL, DANIERU ROBAATO SHIRUBESUTAA, PADLAN EDUARDO AGUSTIN, GROSS MITCHELL STUART
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an amino acid sequence in an immune globulin H-chain or L-chain complementary-deciding area originating from anticoagulation factor monoclonal antibody, or a nucleic acid molecule encoding the area. SOLUTION: This invention provides an amino acid sequence selected from the group consisting of three variable areas for deciding the complementarity in the immune globulin H-chain, and a nucleic acid molecule encoding the complementarity-deciding areas of the immune globulin, and an amino acid sequence selected from the group consisting of three variable areas for deciding the complementarity of the immune globulin L-chain and a nucleic acid molecule encoding the complementarity-deciding areas of the immune globulin. COPYRIGHT: (C)2008,JPO&INPIT