TUMOR ANTIGEN

PROBLEM TO BE SOLVED: To provide a peptide having all the functions of a tumor antigen recognized by HLA-A2-restricted CTL or HLA-A24-restricted CTL, an antigen against the peptide, a compound having interaction with the peptide, a CTL-inducing agent comprising the peptide, a medicinal composition c...

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1. Verfasser: ITO KYOGO
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a peptide having all the functions of a tumor antigen recognized by HLA-A2-restricted CTL or HLA-A24-restricted CTL, an antigen against the peptide, a compound having interaction with the peptide, a CTL-inducing agent comprising the peptide, a medicinal composition containing one or more of these, a method of identification of a compound having interaction with the peptide, a method of inducing the CTL using the peptide, a method of determination of the peptide or the antigen and a reagent kit used in the method of identification and the method of determination. SOLUTION: Description are presented on the determination and the application of the tumor antigen peptide inducing HLA-A2-restricted CTL or HLA-A24-restricted CTL from the peripheral mononuclear blood cells of prostate cancer patients based on the amino acid sequences of protein PSA, PSM and PSCA known as markers for prostate cancer. COPYRIGHT: (C)2008,JPO&INPIT