PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVE SUBSTITUTED WITH CYCLIC AMINO GROUP

PROBLEM TO BE SOLVED: To provide a CRF receptor antagonist and/or a δ-receptor agonist which are effective as a medicine for treating or preventing diseases considered to participate in CRF, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, feeding disorders, hypertension, gastrointestinal disease, drug dependency, cerebral infarction, cerebral ischemia, cerebral edema, head trauma, inflammation, immiity-related diseases, alopecia, irritable intestine syndromes, somnipathy, epilepsy, dermatitis, integrated ataxia, and ache. SOLUTION: The pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group, represented by formula [I], has high affinity with the CRF receptor and/or the δ-receptor, and is effective for diseases estimated to participate in CRF. COPYRIGHT: (C)2007,JPO&INPIT