TRANSGLYCOSYLATION METHOD AND TRANSGLYCOSIDASE

PROBLEM TO BE SOLVED: To provide a new transglycosidase and a transglycosylation method. SOLUTION: The new transglycosylation method comprises the following procedure. In the presence of a protein having endo-α-N-acetyl galactosaminidase activity and transglycosylation activity, a reaction is carrie...

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Hauptverfasser: YAMAGUCHI MASANORI, YAMAMOTO KENJI, OZAWA HAYATO, KATAYAMA TAKANE, KUMAGAI HIDEHIKO, OURA FUSAKO, FUJITA SEIKI, NAGAMINE YOSHIKO, SUZUKI SHUNICHI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a new transglycosidase and a transglycosylation method. SOLUTION: The new transglycosylation method comprises the following procedure. In the presence of a protein having endo-α-N-acetyl galactosaminidase activity and transglycosylation activity, a reaction is carried out to transfer a galactosyl β1→3N-acetyl galactosaminyl α-group from a sugar chain donor containing the galactosyl β1→3N-acetyl galactosaminyl α-group to a sugar chain acceptor. This method is useful in the industries utilizing the glycotechnology, for example, in producing saccharides and glycoproteins. COPYRIGHT: (C)2007,JPO&INPIT