LIQUID COMPOSITION FOR ORAL CAVITY

PROBLEM TO BE SOLVED: To obtain a liquid composition for the oral cavity, which exhibits excellent usability (dischargeability and retention), storage stability (appearance, pH and viscosity) and thickening effect by a Ca ion and sufficiently exhibits improvement effect on retention of a medicinal c...

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Hauptverfasser: MAKINO KAORU, TSUJI KENJI
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creator MAKINO KAORU
TSUJI KENJI
description PROBLEM TO BE SOLVED: To obtain a liquid composition for the oral cavity, which exhibits excellent usability (dischargeability and retention), storage stability (appearance, pH and viscosity) and thickening effect by a Ca ion and sufficiently exhibits improvement effect on retention of a medicinal component in the oral cavity. SOLUTION: The liquid composition for the oral cavity comprises (A) an alginate that has 5-100 mPa s viscosity of 1.0% by mass of an aqueous solution at 20°C and has the content ratio of (M/G ratio) of D-mannuronic acid to L-guluronic acid in the molecule of 0.5-2.0 (mass ratio), (B) xanthan gum, (C) a phosphate represented by general formula (1) MnH3-nPO4(M is Na or K; n is 1, 2 or 3) and (D) water and has the mass ratio of (A) alginate/(B) xanthan gum of 1.0-12.0 and pH 6.0-8.5 at 25°C. COPYRIGHT: (C)2006,JPO&NCIPI
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SOLUTION: The liquid composition for the oral cavity comprises (A) an alginate that has 5-100 mPa s viscosity of 1.0% by mass of an aqueous solution at 20°C and has the content ratio of (M/G ratio) of D-mannuronic acid to L-guluronic acid in the molecule of 0.5-2.0 (mass ratio), (B) xanthan gum, (C) a phosphate represented by general formula (1) MnH3-nPO4(M is Na or K; n is 1, 2 or 3) and (D) water and has the mass ratio of (A) alginate/(B) xanthan gum of 1.0-12.0 and pH 6.0-8.5 at 25°C. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title LIQUID COMPOSITION FOR ORAL CAVITY
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