METHOD FOR PRODUCING OPTICALLY ACTIVE PROPARGYL ALCOHOL

PROBLEM TO BE SOLVED: To provide a new method for producing an optically active 1-substituted-2-propyn-1-ol and an optically active 1-substituted-2-propyn-1-ol ester, especially an optically active 1-cyclohexyl-2-propyn-1-ol and an optically active 1-cyclohexyl-2-propyn-1-ol ester. SOLUTION: The met...

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Hauptverfasser: KASAI YOKO, YOKOO CHIHIRO, SASAKI JIYOUJI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a new method for producing an optically active 1-substituted-2-propyn-1-ol and an optically active 1-substituted-2-propyn-1-ol ester, especially an optically active 1-cyclohexyl-2-propyn-1-ol and an optically active 1-cyclohexyl-2-propyn-1-ol ester. SOLUTION: The method for producing the optically active (-)-(1S)-substituted-2-propyn-1-ol acetate is carried out as follows. A racemic 1-substituted-2-propyn-1-ol is reacted with an enzyme derived from a microbial cell or a microbial culture solution of the genus Aspergillus. COPYRIGHT: (C)2006,JPO&NCIPI