ANTIBODY SPECIFIC TO ACTIVE CASPASE-14 AND METHOD FOR PREPARING THE SAME ANTIBODY

PROBLEM TO BE SOLVED: To provide an antibody specific to an active caspase-14 and to provide a method for preparing the antibody. SOLUTION: The method is a method for preparing the antibody specific to the active caspase-14 produced by cleaving a tyrosine residue at 178th position of an inactive pro...

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Hauptverfasser: KATAGIRI CHIKA, HIBINO TOSHIHIKO, NAKANISHI JIYOUTAROU
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an antibody specific to an active caspase-14 and to provide a method for preparing the antibody. SOLUTION: The method is a method for preparing the antibody specific to the active caspase-14 produced by cleaving a tyrosine residue at 178th position of an inactive procaspase-14 and having the tyrosine residue at 178th position as C terminal. In the preparation method, a peptide containing Gly-Tyr-Ile-Ala-Tyr which is an amino acid sequence at 174-178th of amino acid residue of the inactive type procaspase-14 and containing Tyr residue at C terminal of the above sequence as the C terminal is used as an antigen. COPYRIGHT: (C)2006,JPO&NCIPI