USE OF ANTI-HLA-DR ANTIBODY

PROBLEM TO BE SOLVED: To provide an anti-HLA-DR monoclonal antibody. SOLUTION: The invention provides an antibody or its functional fragment bonding to HLA-DR (antigen) having characteristics of (a) showing a life-prolonging effect on a nonhuman animal carrying cancer cells with HLA-DR expression an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	TAWARA TOMONORI, KATAOKA YUKIRO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an anti-HLA-DR monoclonal antibody. SOLUTION: The invention provides an antibody or its functional fragment bonding to HLA-DR (antigen) having characteristics of (a) showing a life-prolonging effect on a nonhuman animal carrying cancer cells with HLA-DR expression and (b) having a lower immune reaction inhibitory activity than L243; or an antibody or its functional fragment bonding to HLA-DR and showing an immunosuppressive activity comparable to or higher than mouse anti-HLA-DR monoclonal antibody L243 (ATCC HB55). COPYRIGHT: (C)2006,JPO&NCIPI