PROTEIN KINASE C INHIBITOR

PROBLEM TO BE SOLVED: To provide highly isozyme-selective protein kinase C β-1 and β-2 isozyme inhibitors, and also to provide a method for selectively inhibiting protein kinase C isozymes β-1 and β-2. SOLUTION: The β-1 and β-2 isozyme selective inhibitors are the compounds therapeutically useful fo...

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Hauptverfasser:	HEATH JR WILLIAM FRANCIS HEATH, MCDONALD III JOHN H, PAAL MICHAEL, SCHOTTEN THEO, STENZEL WOLFGANG, RUEHTER GERD
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide highly isozyme-selective protein kinase C β-1 and β-2 isozyme inhibitors, and also to provide a method for selectively inhibiting protein kinase C isozymes β-1 and β-2. SOLUTION: The β-1 and β-2 isozyme selective inhibitors are the compounds therapeutically useful for treatment of the disease states associated with diabetes mellitus and its complications as well as other disease states associated with an elevation of the β-1 and β-2 isozymes. COPYRIGHT: (C)2005,JPO&NCIPI