N-ALKYLSULFONYL-SUBSTITUTED AMIDE DERIVATIVE

PROBLEM TO BE SOLVED: To provide an ACC activity inhibitor which is effective for treating obesity, hyperlipemia induced by obesity, abnormal glucose tolerance thought to be based on fatty liver and insulin resistance, diabetes, diabetic complications (diabetic neuropathy, diabetic nephropathy, diab...

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Hauptverfasser: MAEZONO KATSUMI, KONDO NOBUO, NIHEI YUKIO, SUZUKI NOBUYASU, ICHINOSE HIDEHIRO, HATANAKA TOSHIHIRO, OSUMI KOJI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an ACC activity inhibitor which is effective for treating obesity, hyperlipemia induced by obesity, abnormal glucose tolerance thought to be based on fatty liver and insulin resistance, diabetes, diabetic complications (diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy and the like), hypertension, and arteriosclerosis. SOLUTION: An N-alkylsulfonyl-substituted amide derivative of formula (1), its analog or its pharmaceutically acceptable salt has effective action of inhibiting the ACC (acetyl coenzyme A carboxylase) activity. COPYRIGHT: (C)2005,JPO&NCIPI