FLT4 AS RECEPTOR TYROSINE KINASE AND ITS USE IN DIAGNOSIS AND THERAPY

PROBLEM TO BE SOLVED: To provide a diagnostic tool for detecting changes in lymphatic tissues, especially in lymphatic vessels and high endothelial venules in disease states, such as lymphangioma, metastatic lymph nodes and inflammatory, infectious and immunological diseases. SOLUTION: A monoclonal...

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Hauptverfasser:	KORHONEN JAANA, PAJUSOLA KATRI, ALITALO KARI, MUSTONEN TUIJA, MATIKAINEN MARJA-TERTTU, KARNANI PAEIVI, KAIPAINEN ARJA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a diagnostic tool for detecting changes in lymphatic tissues, especially in lymphatic vessels and high endothelial venules in disease states, such as lymphangioma, metastatic lymph nodes and inflammatory, infectious and immunological diseases. SOLUTION: A monoclonal anti-FLT4 antibody is useful as the diagnostic tool for detecting changes in lymphatic tissues, especially in lymphatic vessels and high endothelial venules in disease states, such as lymphangioma, metastatic lymph nodes and inflammatory, infectious and immunological diseases as a specific marker to endothelial cells of lymphatic vessels and high endothelial venules. COPYRIGHT: (C)2005,JPO&NCIPI