PRAVASTATIN SODIUM

PROBLEM TO BE SOLVED: To provide a crystal of pravastatin sodium and a method for preparation of the crystal of pravastatin sodium. SOLUTION: The invention relates to the method for preparing the pravastatin sodium in a crystal state, comprises following steps, (a) preparing a solution containing pr...

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Hauptverfasser: SOMOGYI GYORGY, MOZES NEE SUTO JULIANNA, ILKOY EVA, AMBRUS GABOR, HORVATH GYULA, LANG ILDIKO, ANDOR ATTILA, BARTA ISTVAN, BIRINCSIK LASZLO, BIDLO NEE IGLOY MARGIT, ALBRECHT KAROLY, BOROS SANDOR, KONYA ATTILA, SZABO ISTVAN M, SALAT JANOS, JEKKEL ANTONIA
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a crystal of pravastatin sodium and a method for preparation of the crystal of pravastatin sodium. SOLUTION: The invention relates to the method for preparing the pravastatin sodium in a crystal state, comprises following steps, (a) preparing a solution containing pravastatin and sodium cation in a lower aliphatic alcohol (for example ethanol), (b) adding ethyl acetate to the solution, and (c) crystallizing the pravastatin sodium salt from the solution. COPYRIGHT: (C)2005,JPO&NCIPI