CARRIER CARRYING LIGAND, AND ITS MANUFACTURING METHOD

PROBLEM TO BE SOLVED: To manufacture a carrier having an increased ligand bonding quantity with excellent reproducibility, concerning the carrier including gelatin and gum arabic and carrying the ligand efficiently and a manufacturing method of the carrier. SOLUTION: This manufacturing method of the carrier including the gelatin and the gum arabic and carrying the ligand includes a process for allowing the carrier to carry the ligand following an N-hydroxysuccinimide method including the first reaction for activating a carboxyl group in the carrier including the gelatin and the gum arabic and the second reaction for bonding the ligand to the activated carboxyl group. In this case, the second reaction is performed in a reaction liquid selected from a group comprising an acid solution, an aqueous solution of a salt having a low salt concentration, an aqueous solution of sugars having a low sugar concentration, and pure water. COPYRIGHT: (C)2005,JPO&NCIPI