PROTEIN KINASE C INHIBITOR

PROBLEM TO BE SOLVED: To provide a new and strong protein kinase C inhibitor. SOLUTION: A new and strong bis-indolemaleimide macrocycle derivative is represented by formula (1) and, further, the method for producing the compound, a pharmaceutical preparation containing the compound as an active comp...

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Hauptverfasser:	JIROUSEK MICHAEL R, MCDONALD III JOHN H, HEATH JR WILLIAM FRANCIS, RITO CHRISTOPHER J
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a new and strong protein kinase C inhibitor. SOLUTION: A new and strong bis-indolemaleimide macrocycle derivative is represented by formula (1) and, further, the method for producing the compound, a pharmaceutical preparation containing the compound as an active component and a method for applying the compound to inhibit protein kinase C in mammals are provided. COPYRIGHT: (C)2004,JPO&NCIPI