ALZHEIMER'S DISEASE MODEL

PROBLEM TO BE SOLVED: To provide a model available to screening of substances capable of treating Alzheimer's disease. SOLUTION: Disclosed is a transformed host except human beings including a recombinant polynucleotide having a nucleic acid sequence encoding an allele of a mutant human amyloid...

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Bibliographische Detailangaben
Hauptverfasser:	CHARTIER-HARLIN MARIERISTIN, OWEN MICHAEL JOHN, MULLAN MICHAEL JOHN, HARDY JOHN ANTHONY, GOATE ALISON MARY
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a model available to screening of substances capable of treating Alzheimer's disease. SOLUTION: Disclosed is a transformed host except human beings including a recombinant polynucleotide having a nucleic acid sequence encoding an allele of a mutant human amyloid precursor protein (APP) relating to genetic diatheses of Alzheimer's disease. COPYRIGHT: (C)2004,JPO&NCIPI