NEW CALCIUM-SENSITIVE POTASSIUM CHANNEL PROTEIN

PROBLEM TO BE SOLVED: To provide a gene and a protein encoded by the gene, useful for developing new drugs acting on biological control mechanism and involved in respiratory diseases, and to provide a method for efficiently evaluating activity regulators for the protein. SOLUTION: The gene(DNA) cons...

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Hauptverfasser: IRIE RYOTARO, ISHII SHIZUKO, SUGIYAMA TOMOYASU, WAKAMATSU AI, YAMAZAKI FUMIAKI, ISOGAI TAKAO
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a gene and a protein encoded by the gene, useful for developing new drugs acting on biological control mechanism and involved in respiratory diseases, and to provide a method for efficiently evaluating activity regulators for the protein. SOLUTION: The gene(DNA) consists of a specific base sequence. The calcium-sensitive potassium channel protein is encoded by the DNA. An anti-sense nucleic acid corresponding to the DNA sequence is provided. A method for searching substance(s) regulating the channel function of the protein involving using the protein is provided. A specific antibody against the protein is also provided. COPYRIGHT: (C)2004,JPO&NCIPI