DENTAL DECAY RISK EXAMINATION METHOD

PROBLEM TO BE SOLVED: To provide a dental decay risk examination method for setting all of persons as target specimens regardless of age and saliva quantity. SOLUTION: The genotype of DRB1 in the class II type of an HLA gene group is indentified and preliminarily confirmed. In such a case that a synthetic protein having an amino acid sequence, which comprises preliminarily comfirmed next formula I: Asn Ala Lys Ala Thr Tyr Glu Ala Ala Leu Lys Gln Tyr Glu Ala Asp Leu Ala Ala Val Lys Lys Ala Asn Ala Ala, is set as an antigen, the genotype of DRBI is compared with the genotype related to the degree of a decay risk led out of the magnitude of the antibody titer of secretor immunoglobulin A in human saliva to the antigen to examine the dental decay risk. By this method, the diagnosis of the dental decay risk is performed more widely and accurately, and the value contributing to dental diagnosis become very large. COPYRIGHT: (C)2004,JPO&NCIPI