PHARMACEUTICAL USING COMPOUND HAVING INHIBITORY ACTION ON NEUROCYTE DEATH

PHARMACEUTICAL USING COMPOUND HAVING INHIBITORY ACTION ON NEUROCYTE DEATH

PROBLEM TO BE SOLVED: To obtain an agent useful for treatment and prophylaxis of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), Huntington's disease, Parkinson's disease, Alzheimer's disease, dementia after cerebrovascular disord...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OSUGA HITOSHI, SAKAI HARUMI, IKEDA SHIGEMORI, OKADA YOSHINORI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To obtain an agent useful for treatment and prophylaxis of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), Huntington's disease, Parkinson's disease, Alzheimer's disease, dementia after cerebrovascular disorders or other dementias accompanied with nerve deciduation. SOLUTION: An antineurodegenerative agent comprises a compound selected from the group consisting of 3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine, 5-(4-chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole, 3-(4-chlorophenyl)-4-methyl-5-(1-(2-phenylethyl)piperidin-4-yl)isoxazole and N-methyl-4-(2-cyanophenyl)piperazinyl-3-methylbenzamine and a mixture thereof or a salt thereof. COPYRIGHT: (C)2004,JPO