SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITOR

PROBLEM TO BE SOLVED: To provide a compound and a pharmaceutical composition inhibiting metalloprotease activity, effective in treating lesions and troubles and conditions characterized by excess activity of the metalloprotease. SOLUTION: The metalloprotease activity inhibitor for ameliorating lesio...

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Bibliographische Detailangaben
Hauptverfasser: CHENG MENYAN, BOOKLAND ROGER GUNNARD, NATCHUS MICHAEL GEORGE, PIKUL STANISLAW, DE BISWANATH, TAIWO YETUNDE OLABIST, ALMSTEAD NEIL GREGORY
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a compound and a pharmaceutical composition inhibiting metalloprotease activity, effective in treating lesions and troubles and conditions characterized by excess activity of the metalloprotease. SOLUTION: The metalloprotease activity inhibitor for ameliorating lesions, troubles and condition characterized by excess activity of the metalloprotease comprises a compound expressed by formula (I) or its optical isomer, diastereomer or enantiomer, or their pharmaceutically-acceptable salt, a biodegradable amide, ester or imide. And the pharmaceutical composition containing the same is prepared. COPYRIGHT: (C)2004,JPO